Elsevier is pleased to announce that beginning with Volume 104 (2010) it will assume publication of the Annals of Allergy, Asthma & Immunology, the official journal of the American College of Allergy, Asthma & Immunology (ACAAI). The i>Annals of Allergy, Asthma & Immunology, published since 1942, will continue under the leadership of Editor Gailen D. Marshall, MD, PhD and a distinguished editorial board. The journal provides solid, peer-reviewed coverage of current clinical science (both research and practice-based) that is readily applicable to both the clinician and the researcher in the fields of allergy, asthma, and immunology. Each monthly issue also provide opportunities to participate in accredited continuing medical education activities to enhance overall clinical proficiency.
As flu season got underway this fall, Dr. Catherine Monteleone, an allergist, noticed that her office started to receive an unusually high number of calls from people with egg allergy. They previously had avoided flu vaccines because of their sensitivity to eggs. This year, with all the attention being paid to the novel H1N1 influenza, those patients want to be protected against flu, and they contacted her to find out if they are candidates for inoculation. "Seasonal and H1N1 flu vaccines are produced in chicken embryos eggs so people who have egg allergy generally avoid them, " Monteleone, an associate professor of medicine at the UMDNJ-Robert Wood Johnson Medical School, explained.
Scientists at Johns Hopkins and their colleagues have developed sugar-coated polymer strands that selectively kill off cells involved in triggering aggressive allergy and asthma attacks. Their advance is a significant step toward crafting pharmaceuticals to fight these often life-endangering conditions in a new way. For more than a decade, a team led by Bruce S. Bochner, M.D., director of the Division of Allergy and Clinical Immunology at the Johns Hopkins University School of Medicine, has studied a unique protein known as Siglec-8. This protein, whose name is an acronym for Sialic Acid-binding, Immunoglobulin-like LECtin number 8, is present on the surfaces of a few types of immune cells, including eosinophils, basophils and mast cells.
Circassia Announces Successful Results From Phase II Clinical Study Of ToleroMune R Cat Allergy Therapy
Circassia Ltd, a specialty biopharmaceutical company focused on allergy, announced positive results from a recently completed phase II clinical study of its ToleroMune(R) cat allergy therapy, which successfully identified the optimal dosing regimens to progress into late-stage development. The clinical trial, which was the first of its kind in the field of cat allergy immunotherapy, showed that Circassia's ToleroMune treatment was extremely well tolerated and greatly reduced sufferers' symptoms. Circassia conducted the double-blind study in Canada, where 121 subjects with confirmed cat allergies were randomised to receive placebo or one of four different treatment regimes with standardised doses of ToleroMune.
Sublingual immunotherapy for the treatment of allergy symptoms caused by a wide variety of environmental inhalants has been effectively used in Europe. It should be employed to further treatment of allergies in the United States, where averse symptoms are largely undertreated, according to an invited article in the Apr 2009 issue of Otolaryngology-Head and Neck Surgery. A response to the article, published in the equivalent daybook issue, expresses cautious optimism, but calls for fresh research. Sublingual immunotherapy (SLIT) involves the administering of an allergen thought under the tongue, which in era reduces the patient's sensitivity to those allergens.
If you're one of the millions who dread the spring allergy season, matters are looking up. A research glance at appearing in the May 2009 affair of the Journal of Leukocyte Biology shows how a side of American scientists hold identified a formerly unknown cellular switch that turns allergies and asthma both on and off. Equally important, this study too suggests that at least for some people with asthma and allergies, their problems might be caused by genes that prevent this switch from working properly. Taken together, this information is an conspicuous aboriginal step toward new medications that address the root causes of allergies, asthma and other consonant diseases.
ImVisioN Therapeutics AG, a biopharmaceutical association pioneering intralymphatic immunotherapy (ILIT™ ), nowadays announced that it has obtained cold Episode I clinical results for its first place product, IVN201 (Cat-MAT), an immunotherapeutic product for the treatment of cat dander allergy. The study was conducted from August 2008 to Step 2009 in a complete of 20 patients with allergy to cat dander. The results demonstrated an excellent safety profile and exceptional tolerability in hypersensitive patients. In addition, the IVN201 program showed the cardinal signs of efficacy as measured by several clinical parameters. The double-blind, placebo-controlled clinical glance at was conducted at the University Hospital in Zurich, Switzerland.
Avoiding foods may cause besides harm than good / Elimination diets can only assist children who have food sensitivity The number of children who have eczema has risen - one in five children are like now affected by this skin condition, which is often associated with an allergy. Researchers are not yet certain what is causing this growing problem. Many people deem that certain foods are responsible, or at least make the symptoms worse. However, in break condign published, the German Institute for Quality and Efficiency in Health Keeping (IQWiG) stresses that parents should be cautious about eliminating considerable foods like milk from their baby's or child's diet.
Considerably exceeding family than formerly believed are allergic to the most common fragrance ingredient used in shampoos, conditioners and soap. A thesis presented at the Sahlgrenska Academy, University of Gothenburg, Sweden inaugurate that over 5% of those who underwent patch testing were allergic to the air oxidized conformation of the fragrance ingredient linalool. "I would suspect that about 2% of the comprehensive population of Sweden are sensitive to air oxidized linalool. That may not sound ideal much, on the contrary it is serious since linalool is so widely used as a perfume ingredient. Linalool is found in 60-80 percent of the perfumed hygiene products, washing up liquids and household cleaning agents that can be bought in the nearest supermarket, and it can be difficult for crowd who are allergic to avoid these products", says dermatologist Johanna BrĂ red Christensson, author of the thesis.
Alcon (NYSE: ACL) and the Asthma and Allergy Foundation of America (AAFA) hold joined forces to spread the word approximately seasonal allergies and treatment over media outlets today. As the spring allergy season comes into full force, it is considerable for allergy sufferers to understand their treatment options. Seasonal allergies affect about 40 to 50 million people in the United States alone and are one of the top causes of absenteeism from work and school. "There are some dissimilar concepts and fashionable treatments for the springtime problems people are already experiencing, " said Bobby Lanier, M.D. and clinical professor at the University of North Texas Health Science Center.