Testing has begun on a device that can sniff out the presence of disease by smell, thanks to a 1.3 million pound award from the Wellcome Trust. OdoReader, developed by Chris Probert from the University of Bristol and Norman Ratcliffe from the University of the West of England, uses pioneering technology to rapidly diagnose Clostridium difficile, by 'reading' the odour of stool samples. Clostridium difficile may cause severe diarrhoea, especially amongst hospitalised patients. With the help of University Hospitals Bristol NHS Foundation Trust, the technology enables gasses emitted from faeces to be analysed in under an hour, leading to a rapid and inexpensive diagnosis.
U.N. Secretary-General Ban Ki-moon on Wednesday asked former President Bill Clinton, currently the U.N. special envoy for Haiti, to oversee aid and rebuilding efforts in Haiti, CNN reports (2/3). Ban "specifically asked President Clinton to assume a leadership role in coordinating international aid efforts from emergency response to the reconstruction of Haiti, " U.N. spokesperson Martin Nesirky said, Reuters reports. "There's an awful lot of goodwill out there, an unprecedented flow of aid and good intentions and cash, and the idea is to ensure that that comes together in the right way, " Nesirky said. In this role, Clinton will be charged with coordinating the work of NGOs, private groups, governments and U.
A new report, Adult Immunization: Shots to Save Lives, released by the Trust for America's Health (TFAH), the Infectious Diseases Society of America (IDSA), and the Robert Wood Johnson Foundation (RWJF) found that more than 30 percent of adults ages 65 and older had not been immunized against pneumonia in 36 states as of 2008. The U.S. Centers for Disease Control and Prevention (CDC) and other experts recommend that all seniors should be vaccinated against pneumonia, which is a one-time shot for most individuals, since seniors who get the seasonal flu are at risk for developing pneumonia as a complication. Nationally, 33.1 percent of seniors had not been immunized against pneumonia, and even in the state with the highest immunization rate - Oregon - more than one quarter (26.
New Research Uncovers Molecular Firing Squad Through Which Overeating Destroys Normal Metabolism And Sets Stage For Diabetes
Overeating in mice triggers a molecule once considered to be only involved in detecting and fighting viruses to also destroy normal metabolism, leading to insulin resistance and setting the stage for diabetes. The new study, led by researchers at the Harvard School of Public Health (HSPH), specifically links together the immune system and metabolism, a pairing increasingly suspected in diseases that include - in addition to diabetes - heart disease, fatty liver, cancer, and stroke. Understanding how to regulate the molecule through targeted drugs or nutrients could eventually change the way these diseases are prevented and treated in humans. The study will publish in the February 5, 2010, issue of Cell.
Bacteria that infect chronic wounds can be deadly to maggot 'biosurgeons' used to treat the lesions, show researchers writing in the journal Microbiology. The findings could lead to more effective treatment of wounds and the development of novel antibiotics. Scientists from the Copenhagen Wound Healing Centre, Statens Serum Institut and the University of Copenhagen in Denmark showed that maggots applied to simulated wounds heavily infected with the bacterium Pseudomonas aeruginosa, were unable to treat the wound and were left dead after 20 hours. Chronic wounds, such as leg ulcers, affect 1% of the Western population and are painful and difficult to treat.
This year, the message for World Cancer Day, 4th February, is "Cancer can be prevented too", with experts suggesting that 40 per cent of the 12.4 million cancers diagnosed and 7.6 million cancer deaths worldwide could be prevented if we applied what we know about avoiding infections and changing lifestyles. The International Union Against Cancer (UICC) and the World Health Organization (WHO) who are marking World Cancer Day, said such reductions could be within our reach were we to apply "evidence-based cancer prevention strategies". If someone came up with a single vaccine or drug that was proven to cure 40 per cent of all cancers we would all be dancing in the streets, yet in effect this is what we have says the UICC, except it isn't in one tablet, it's in lots of different bits of knowledge and strategies, we just need to apply them effectively and comprehensively.
HEALTH CARE - Maximizing mammography. .. .. . Mammograms could conceivably save more lives with a technology being developed by researchers at Oak Ridge National Laboratory and the University of Chicago. The proposed system would allow doctors to quickly identify trends specific to an individual patient and also match images and text to a database of known cancerous and pre-cancerous conditions. "Our goal is to develop a decision and support system that helps doctors and patients, " said Robert Patton of ORNL's Computational Sciences and Engineering Division. "There is a wealth of existing information that doctors could be using but with time and resource constraints it is virtually impossible.
Dr. Kim Orth, associate professor of molecular biology at UT Southwestern Medical Center, has been honored with the 2010 Norman Hackerman Award in Chemical Research for pioneering work focusing on the mechanisms bacteria use to cause disease. The Houston-based Welch Foundation, one of the nation's oldest and largest sources of private funding for basic research in chemistry, presents the award annually to honor up-and-coming scientists at Texas institutions. Recipients are recognized for expanding the frontiers of chemistry through their innovative research. First bestowed in 2002, the award pays tribute to the late Norman Hackerman, a noted scientist and longtime chairman of the foundation's scientific advisory board.
Study Finds Association Between Genes That Regulate Maternal Inflammatory Response, Bacterial Vaginosis And Preterm Delivery
In a study presented at the Society for Maternal-Fetal Medicine's (SMFM) annual meeting, The Pregnancy Meeting™ in Chicago, researchers showed the use of haplotype tagging (hap-tag) single-nucleotide polymorphisms (SNPs) to study the relationship between genetic predispositions, an environmental factor - bacterial vaginosis, and preterm birth. Studies previously demonstrated that genetic variation within genes that regulate the maternal inflammatory response are associated with an increased risk of spontaneous preterm delivery (SPTD). The new study sought to determine if an environmental exposure associated with maternal inflammation, bacterial vaginosis (BV), modifies these genetic susceptibilities.
New research shows that two different antimicrobial regimens for treating buruli ulcer (Mycobacterium ulcerans infection) are effective at treating early, limited disease. This is the conclusion of an Article published Online First ( http://www.thelancet.com ) and in an upcoming edition of The Lancet -written by Professor Tjip S van der Werf, University Medical Centre Groningen, Netherlands, and colleagues. Buruli ulcer is classed a neglected tropical disease. The early stage of infection is characterised by a painless nodule, with lesions developing on the skin, and occasionally in adjacent bone, as the disease progresses. Surgery was the standard treatment for Buruli ulcer disease until WHO issued provisional guidelines in 2004 recommending treatment with antimicrobial drugs (streptomycin and rifampicin) in addition to surgery.